It can also be used for insomnia, symptoms of the common cold, tremor in parkinsonism, and nausea. Find patient medical information for Benadryl Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The usual prescription for flight anxiety has been Xanax. I can't seem to get rid of the vomiting. Diphenhydramine is an antihistamine mainly used to treat allergies. Please help me if you have any suggestions of what I should do. How does benadryl help with nausea? Oddly enough, they are actually basically the same drug. I am about 10 weeks pregnant and I have horrible morning sickness. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. The following information is NOT intended to endorse any particular medication. ... Benadryl, commonly used for allergies (itchy eyes, runny nose,sneezing) Benadryl can be bought over the counter for as needed use. It is used by mouth, injection into a vein, injection into a muscle, or applied to the skin. As neither Dramamine nor Benadryl help the anxiety or nausea I get when flying, what else might work? 1. Benedril is diphenhydramine (bonded in a hydrochloride salt formulation). An understanding of the pathophysiology of nausea and the mechanisms of antiemetics can help family physicians improve the cost-effectiveness and efficacy of therapy. User Reviews for Dramamine to treat Nausea/Vomiting. I hate it because I'm working and I have to keep running to the bathroom to throw up (Sorry if it sounds gross). Benadryl is a great medication for use in dogs with mild-to-moderate allergies. Thanks for A2A. Maximal effect is typically around two hours after a dose, and effects can last for up to seven hours.