Needham CA, McPherson KA, Webb KH.

Study: Acad Emerg Med.

WHAT ARE LIKELIHOOD RATIOS? Diagnosis . likelihood ratio (LR). Recently, the U.S. Food and Drug Administration (FDA) approved molecular tests that can detect genetic material from group A strep bacteria in throat swab specimens in less than 8 minutes. Evidence Based Medicine: Articles of Diagnosis Duke University School of Medicine EBM Course February 6, 2014 Jamie Fox, MD David Ming, MD Departments of Internal Medicine and Pediatrics . J Clin Microbiol 1998;36:3468-3473.

Rapid Testing. Why conduct diagnostic tests? Streptococcal pharyngitis: impact of a high-sensitivity antigen test on physician outcome.
4. A rapid strep test, also known as a rapid antigen detection test (RADT), can detect group A strep antigens. A diagnostic test is useful only if the result substan-See related article, p. 565. racy of elements of the clinical evaluation are to be used in patient care and decisionmaking. 6 Using an appropriate pathogen-focused antibiotic or narrowing empirical therapy may decrease cost, drug adverse events, and the threat of antibiotic resistance. J Fam Pract 2000;49:34-43. The LR can be derived from the test’s sensitivity and specificity 1 or from the primary data as reported in studies on diagnostic test accuracy. However, other rapid tests with similar demands, such as the rapid strep test, have found a place in many physicians' offices. 2000 Oct;7(10):1104-9. PMID: 11015241. Webb KH, Needham CA, Kurtz SR. Use of a high-sensitivity rapid strep test without culture confirmation of negative results: 2 years’ experience. Early and rapid diagnosis of CAP would allow more directed therapy and confidence in appropriate treatment for a majority of patients. Results are available in 10-20 minutes. The pretest likelihood of GAS pharyngitis was the primary exposure of ... All children with suspected pharyngitis underwent a rapid chromatographic immunoassay test (ACON Strep A Rapid Test Device, Throat Swab, ACON Laboratories, Inc, San Diego, USA) for GAS, performed at the point of care by trained physicians.

Sensitivity: Specificity: Comments, Study: Physical Exam: 71%: 77%: all 4: Tender Adenopathy, Pharyngeal Exudates, Pharyngeal Erythema, and Enlarged Tonsils. 5.